Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Pax6  paired box 6   (Synonyms: 1500038E17Rik, AEY11, Dey, Dickie's small eye, Gsfaey11, Pax-6)
Results	Reference
1	J:273860 Andreu-Cervera A, Anselme I, Karam A, Laclef C, Catala M, Schneider-Maunoury S, The Ciliopathy Gene Ftm/Rpgrip1l Controls Mouse Forebrain Patterning via Region-Specific Modulation of Hedgehog/Gli Signaling. J Neurosci. 2019 Mar 27;39(13):2398-2415
1	J:127387 Armentano M, Chou SJ, Tomassy GS, Leingartner A, O'Leary DD, Studer M, COUP-TFI regulates the balance of cortical patterning between frontal/motor and sensory areas. Nat Neurosci. 2007 Oct;10(10):1277-86
1	J:186055 Ashique AM, Choe Y, Karlen M, May SR, Phamluong K, Solloway MJ, Ericson J, Peterson AS, The Rfx4 transcription factor modulates Shh signaling by regional control of ciliogenesis. Sci Signal. 2009;2(95):ra70
1	J:96233 Backman M, Machon O, Mygland L, van den Bout CJ, Zhong W, Taketo MM, Krauss S, Effects of canonical Wnt signaling on dorso-ventral specification of the mouse telencephalon. Dev Biol. 2005 Mar 1;279(1):155-68
1	J:231655 Barber M, Arai Y, Morishita Y, Vigier L, Causeret F, Borello U, Ledonne F, Coppola E, Contremoulins V, Pfrieger FW, Tissir F, Govindan S, Jabaudon D, Proux-Gillardeaux V, Galli T, Pierani A, Migration Speed of Cajal-Retzius Cells Modulated by Vesicular Trafficking Controls the Size of Higher-Order Cortical Areas. Curr Biol. 2015 Oct 5;25(19):2466-78
1	J:89364 Bulgakov OV, Eggenschwiler JT, Hong DH, Anderson KV, Li T, FKBP8 is a negative regulator of mouse sonic hedgehog signaling in neural tissues. Development. 2004 May;131(9):2149-59
1	J:250493 Bunt J, Lim JW, Zhao L, Mason S, Richards LJ, PAX6 does not regulate Nfia and Nfib expression during neocortical development. Sci Rep. 2015 May 29;5:10668
1	J:110657 Cheng X, Hsu CM, Currle DS, Hu JS, Barkovich AJ, Monuki ES, Central roles of the roof plate in telencephalic development and holoprosencephaly. J Neurosci. 2006 Jul 19;26(29):7640-9
1	J:35802 Chiang C, Litingtung Y, Lee E, Young KE, Corden JL, Westphal H, Beachy PA, Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature. 1996 Oct 3;383(6599):407-13
1	J:59749 Dietrich S, Schubert FR, Gruss P, Lumsden A, The role of the notochord for epaxial myotome formation in the mouse. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):601-16
1*	J:48135 Fernandez AS, Pieau C, Reperant J, Boncinelli E, Wassef M, Expression of the Emx-1 and Dlx-1 homeobox genes define three molecularly distinct domains in the telencephalon of mouse, chick, turtle and frog embryos: implications for the evolution of telencephalic subdivisions in amniotes. Development. 1998 Jun;125(11):2099-111
1	J:194843 Ferri A, Favaro R, Beccari L, Bertolini J, Mercurio S, Nieto-Lopez F, Verzeroli C, La Regina F, De Pietri Tonelli D, Ottolenghi S, Bovolenta P, Nicolis SK, Sox2 is required for embryonic development of the ventral telencephalon through the activation of the ventral determinants Nkx2.1 and Shh. Development. 2013 Mar;140(6):1250-61
1	J:170384 Fischer T, Faus-Kessler T, Welzl G, Simeone A, Wurst W, Prakash N, Fgf15-mediated control of neurogenic and proneural gene expression regulates dorsal midbrain neurogenesis. Dev Biol. 2011 Feb 15;350(2):496-510
1*	J:98371 Gotz K, Briscoe J, Ruther U, Homozygous Ft embryos are affected in floor plate maintenance and ventral neural tube patterning. Dev Dyn. 2005 Jun;233(2):623-30
1	J:108511 Griesel G, Treichel D, Collombat P, Krull J, Zembrzycki A, van den Akker WM, Gruss P, Simeone A, Mansouri A, Sp8 controls the anteroposterior patterning at the midbrain-hindbrain border. Development. 2006 May;133(9):1779-87
1	J:210692 Hagglund AC, Berghard A, Carlsson L, Canonical Wnt/beta-catenin signalling is essential for optic cup formation. PLoS One. 2013;8(12):e81158
1*	J:49282 Hammond KL, Hanson IM, Brown AG, Lettice LA, Hill RE, Mammalian and Drosophila dachshund genes are related to the Ski proto-oncogene and are expressed in eye and limb. Mech Dev. 1998 Jun;74(1-2):121-31
1*	J:74492 Heanue TA, Davis RJ, Rowitch DH, Kispert A, McMahon AP, Mardon G, Tabin CJ, Dach1, a vertebrate homologue of Drosophila dachshund, is expressed in the developing eye and ear of both chick and mouse and is regulated independently of Pax and Eya genes. Mech Dev. 2002 Feb;111(1-2):75-87
1*	J:99098 Hester M, Thompson JC, Mills J, Liu Y, El-Hodiri HM, Weinstein M, Smad1 and Smad8 function similarly in mammalian central nervous system development. Mol Cell Biol. 2005 Jun;25(11):4683-92
1*	J:143555 Jiang B, Kumar SD, Loh WT, Manikandan J, Ling EA, Tay SS, Dheen ST, Global gene expression analysis of cranial neural tubes in embryos of diabetic mice. J Neurosci Res. 2008 Dec;86(16):3481-93
1	J:143527 Kala K, Haugas M, Lillevali K, Guimera J, Wurst W, Salminen M, Partanen J, Gata2 is a tissue-specific post-mitotic selector gene for midbrain GABAergic neurons. Development. 2009 Jan;136(2):253-62
1	J:58952 Kioussi C, O'Connell S, St-Onge L, Treier M, Gleiberman AS, Gruss P, Rosenfeld MG, Pax6 is essential for establishing ventral-dorsal cell boundaries in pituitary gland development. Proc Natl Acad Sci U S A. 1999 Dec 7;96(25):14378-82
1*	J:91012 Kurokawa D, Takasaki N, Kiyonari H, Nakayama R, Kimura-Yoshida C, Matsuo I, Aizawa S, Regulation of Otx2 expression and its functions in mouse epiblast and anterior neuroectoderm. Development. 2004 Jul;131(14):3307-17
1*	J:107595 Landsberg RL, Awatramani RB, Hunter NL, Farago AF, DiPietrantonio HJ, Rodriguez CI, Dymecki SM, Hindbrain rhombic lip is comprised of discrete progenitor cell populations allocated by Pax6. Neuron. 2005 Dec 22;48(6):933-47
1*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1*	J:74238 Marin O, Baker J, Puelles L, Rubenstein JL, Patterning of the basal telencephalon and hypothalamus is essential for guidance of cortical projections. Development. 2002 Feb 1;129(3):761-73
1	J:102847 Matt N, Dupe V, Garnier JM, Dennefeld C, Chambon P, Mark M, Ghyselinck NB, Retinoic acid-dependent eye morphogenesis is orchestrated by neural crest cells. Development. 2005 Nov;132(21):4789-800
1	J:78037 Muzio L, DiBenedetto B, Stoykova A, Boncinelli E, Gruss P, Mallamaci A, Conversion of cerebral cortex into basal ganglia in Emx2(-/-) Pax6(Sey/Sey) double-mutant mice. Nat Neurosci. 2002 Aug;5(8):737-45
1*	J:309436 Parish EV, Mason JO, Price DJ, Expression of Barhl2 and its relationship with Pax6 expression in the forebrain of the mouse embryo. BMC Neurosci. 2016 Nov 25;17(1):76
1	J:121968 Ruzhynsky VA, McClellan KA, Vanderluit JL, Jeong Y, Furimsky M, Park DS, Epstein DJ, Wallace VA, Slack RS, Cell cycle regulator E2F4 is essential for the development of the ventral telencephalon. J Neurosci. 2007 May 30;27(22):5926-35
1	J:339441 Sansom SN, Hebert JM, Thammongkol U, Smith J, Nisbet G, Surani MA, McConnell SK, Livesey FJ, Genomic characterisation of a Fgf-regulated gradient-based neocortical protomap. Development. 2005 Sep;132(17):3947-61
1*	J:55154 Schwarz M, Alvarez-Bolado G, Dressler G, Urbanek P, Busslinger M, Gruss P, Pax2/5 and Pax6 subdivide the early neural tube into three domains. Mech Dev. 1999 Apr;82(1-2):29-39
1	J:56417 Shum AS, Poon LL, Tang WW, Koide T, Chan BW, Leung YC, Shiroishi T, Copp AJ, Retinoic acid induces down-regulation of Wnt-3a, apoptosis and diversion of tail bud cells to a neural fate in the mouse embryo. Mech Dev. 1999 Jun;84(1-2):17-30
1	J:325356 Su-Feher L, Rubin AN, Silberberg SN, Catta-Preta R, Lim KJ, Ypsilanti AR, Zdilar I, McGinnis CS, McKinsey GL, Rubino TE Jr, Hawrylycz MJ, Thompson C, Gartner ZJ, Puelles L, Zeng H, Rubenstein JLR, Nord AS, Single cell enhancer activity distinguishes GABAergic and cholinergic lineages in embryonic mouse basal ganglia. Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2108760119
1*	J:70745 Suda Y, Hossain ZM, Kobayashi C, Hatano O, Yoshida M, Matsuo I, Aizawa S, Emx2 directs the development of diencephalon in cooperation with Otx2. Development. 2001 Jul;128(13):2433-50
1	J:55842 Sussel L, Marin O, Kimura S, Rubenstein JL, Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum. Development. 1999 Aug;126(15):3359-70
1*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1*	J:65597 van Raamsdonk CD, Tilghman SM, Dosage requirement and allelic expression of PAX6 during lens placode formation. Development. 2000 Dec;127(24):5439-48
1*	J:1914 Walther C, Gruss P, Pax-6, a murine paired box gene, is expressed in the developing CNS. Development. 1991 Dec;113(4):1435-49
1	J:101730 Yoshimoto A, Saigou Y, Higashi Y, Kondoh H, Regulation of ocular lens development by Smad-interacting protein 1 involving Foxe3 activation. Development. 2005 Oct;132(20):4437-48
1	J:319920 Ypsilanti AR, Pattabiraman K, Catta-Preta R, Golonzhka O, Lindtner S, Tang K, Jones IR, Abnousi A, Juric I, Hu M, Shen Y, Dickel DE, Visel A, Pennachio LA, Hawrylycz M, Thompson CL, Zeng H, Barozzi I, Nord AS, Rubenstein JL, Transcriptional network orchestrating regional patterning of cortical progenitors. Proc Natl Acad Sci U S A. 2021 Dec 21;118(51):e2024795118
1	J:66590 Yun K, Potter S, Rubenstein JL, Gsh2 and Pax6 play complementary roles in dorsoventral patterning of the mammalian telencephalon. Development. 2001 Jan;128(2):193-205
1	J:156965 Zhang W, Mulieri PJ, Gaio U, Bae GU, Krauss RS, Kang JS, Ocular abnormalities in mice lacking the immunoglobulin superfamily member Cdo. FEBS J. 2009 Oct;276(20):5998-6010
1*	J:136711 Zhao H, Yang T, Madakashira BP, Thiels CA, Bechtle CA, Garcia CM, Zhang H, Yu K, Ornitz DM, Beebe DC, Robinson ML, Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation. Dev Biol. 2008 Jun 15;318(2):276-88